Jungle Jim is asked to find a young woman who supposedly lives in the jungle with her pet tiger. It's believed that she may be the daughter of Mr. and Mrs. John Martindale, explorers who long ago who were looking for the lagoon of the dead, a place where legend has it witch doctors held human sacrifices. Some of the locals, particularly the witch doctor Hakim, believe she is a she-devil who is out to cause them harm. As well Barton, an gold-hunting explorer, is also looking for the girl and lagoon which he believes contains a treasure of gold. Jungle Jim will have to fight several jungle animals along the way before he rescues the girl from Hakim.